Hyperparathyroidism is a condition when the parathyroid hormone is elevated.  This may be the cause of kidney stones, but most cases of hyperparathyroidism cause an elevated blood calcium level without symptoms.  Elevated calcium can be related to symptoms of fatigue, depression, muscle pain, bone pain, or changes in the bones also.  People with fibromyalgia symptoms have symptoms similar to those with hyperparathyroidism. 

Testing for hyperparathyroidism

People with hyperparathyroidism may have an elevated parathyroid hormone or ionized calcium level in the blood.  Sometimes urinary calcium levels are elevated.  At the same time, tests for creatinine, vitamin D, alkaline phosphatase, phosphate, and magnesium should be normal.

Causes of hyperparathyroidism

Elevated parathyroid hormone can be caused by side effects of medicines, changes in the parathyroid gland, certain kinds of cancer, and changes in calcium metabolism.

Treatment of hyperparathyroidism

Clinical observation is an important part of caring for this condition.  This may include lab tests or bone density monitoring.  Some patients use a medicine to protect the bone density in this condition. Others use a medicine to help keep calcium levels low.  Surgery of the parathyroid gland is also sometimes helpful.


Marx SJ, N Engl J Med 2000 Dec 21: 343(25) 1863-75, Hyperparathyroid and hypoparathyroid disorders

Ferrari and Russell, Clin Rheum 2015 Jul 34(7): 1279-83, Prevalence of primary hyperparathyroidism in a referred sample of fibromyalgia patients