Sjogren syndrome

Sjögren syndrome is in autoimmune disorder. It may interfere with the tear glands, salivary glands, and cause symptoms of fatigue, muscle pain, or cognitive dysfunction. Rheumatoid arthritis and systemic lupus are associated with this condition.

The diagnosis of Sjogren’s syndrome is suspected in people with dry eyes or mouth, enlargement of the parotid glands, unexplained cavities, or blood test abnormalities. These are often blood tests for SSA or SSB antibodies. There is no specific test for Sjögren syndrome, it is a condition that requires exclusion of other diagnoses.

The diagnostic criteria for Sjögren syndrome in 2016 have been suggested as the following:

An abnormal blood test for Anti-SSA antibody and/or lymphocyte infiltration of the salivary glands

an abnormal Schirmer’s test or decreased salivation rate

and signs and symptoms of Sjogren’s syndrome.

Some medical conditions exclude this diagnosis. These include: sarcoidosis, lymphoma, AIDS, hepatitis C, radiation treatment to the head or neck, graft versus host disease, or medications that cause dry mouth

Treatment of Sjogren’s syndrome depends on the symptoms that each patient has. This may be an immune system inhibitor, symptomatic remedies for dry eyes or dry mouth, and occasionally anti-inflammatory medications for muscle or joint pain.

References

Shiboski, CH. et al., 2016 American College of Rheumatology: rheumatism classification criteria for primary Sjogren’s syndrome, Annals of Rheumatologic disease, 2016, October 26